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Question 1 of 3
1. Question
TEXT A
The International Agency for Research on Cancer (IARC), which is the specialised cancer agency of the World Health Organization, has declared aspartame may be a possible carcinogenic hazard to humans.
Another branch of the WHO, the Joint WHO and Food and Agriculture Organization’s Expert Committee on Food Additives has assessed the risk and developed recommendations on how much aspartame is safe to consume. They have recommended the acceptable daily intake be 0 to 40mg per kilo of body weight, as we currently have in Australia.
A hazard is different to a risk. The hazard rating means it’s an agent that is capable of causing cancer; a risk measures the likelihood it could cause cancer. So what does this hazard assessment mean for you?
TEXT B
Aspartame is an artificial sweetener that is 200 times sweeter than sugar, but without any kilojoules.
It’s used in a variety of products including carbonated drinks such as Coke Zero, Diet Coke, Pepsi Max and some home brand offerings. You can identify aspartame in drinks and foods by looking for additive number 951.
Food products such as yogurt and confectionery may also contain aspartame, but it’s not stable at warm temperatures and thus not used in baked goods.
Commercial names of aspartame include Equal, Nutrasweet, Canderel and Sugar Twin. In Australia the acceptable daily intake is 40mg per kilo of body weight per day, which is about 60 sachets.
In America the acceptable daily intake has been set at 75 sachets.
TEXT C
IARC has four categories (groupings) available for potential substances (or as they are referred to by IARC, “agents”) that may cause cancer.
What does each grouping mean?
Group 1 Carcinogenic to humans: an agent in this group is carcinogenic, which means there is convincing evidence from human studies and we know precisely how it causes cancer. There are 126 agents in this group, including tobacco smoking, alcohol, processed meat, radiation and ionising radiation.
Group 2a Probably carcinogenic to humans: there are positive associations between the agent and cancer in humans, but there may still be other explanations for the association which were not fully examined in the studies. There are 95 agents in this group, including red meat, DDT insecticide and night shift work.
Group 2b Possibly carcinogenic in humans: this means limited evidence of causing cancer in humans, but sufficient evidence from animal studies, or the mechanism of how the agent may be carcinogenic is well understood. This basically means the current evidence indicates an agent may possibly be carcinogenic, but more scientific evidence from better conducted studies is needed. There are now 323 agents in this group, including aloe vera (whole leaf extract), ginkgo biloba and lead.
Group 3 Not classifiable as a carcinogen: there’s not enough evidence from humans or animals, and there is limited mechanistic evidence of how it may be a carcinogen. There are 500 agents in this group.
TEXT D
So do I have to give up my diet soft drink habit? For a 70kg person you would need to consume about 14 cans (over 5 litres) of soft drink sweetened with aspartame a day to reach the acceptable daily intake.
But we need to remember there may also be aspartame added in other foods consumed. So this is an unrealistic amount to consume, but not impossible.
We also need to consider all the evidence on aspartame together. The foods we typically see aspartame in are processed or ultra-processed, which have recently also been shown to be detrimental to health.
And artificial sweeteners (including aspartame) can make people crave more sugar, making them want to eat more food, potentially causing them to gain more weight.
All together, this indicates we should be more careful about the amount of artificial sweeteners we consume, since they do not provide any health benefits, and have possible adverse effects.
But overall, from this evidence, drinking the occasional or even daily can of a diet drink is safe and probably not a cancer risk.
Correction: this article originally stated each serve of soft drink in a study was linked to a 6% increased risk of liver cancer, however it was each additional serve per week. This has been amended.
Questions 1-7
For each of the questions, 1-7, decide which text (A, B, C or D) the information comes from. You may use any letter more than once.
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1. Disparity between the hazard assessment and the acceptable daily intake?
2. Daily intake in America of aspartame?
3. What is the difference between a hazard and a risk in the context of the IARC’s assessment of aspartame as a possible carcinogenic hazard to humans.
4. Correction made regarding to original article regarding aspartame and liver cancer?
5. Carcinogenic grouping?
6. Stability of aspartame in yogurt?
7. Acceptable intake in Australia?
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Question 2 of 3
2. Question
Questions 8-14
Answer each of the questions, 8-4, with a word or short phrase from one of the texts. Each answer may include words, number of the both. Your answers should be correctly spelled.
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8. Aspartame is an artificial sweetener that is times sweeter than sugar, but without any kilojoules.
9. In Australia, the acceptable daily intake of aspartame is milligrams per kilogram of body weight per day.
10. The International Agency for Research on Cancer (IARC) has categories for potential substances that may cause cancer.
11. Group 1 agents according to IARC are classified as .
12. For a 70kg person, approximately cans (over 5 litres) of soft drink sweetened with aspartame a day would be needed to reach the acceptable daily intake.
13. Artificial sweeteners like aspartame may make people crave more sugar, potentially causing them to gain weight.
14. Aspartame is commonly found in or ultra processed food
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Question 3 of 3
3. Question
Questions 15-20
Complete each of the sentences, 15- 20, with a word or short phrase from one of the texts. Each answer may include words, number or both. Your answers should be correctly spelled
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15. The acceptable daily intake of aspartame in America is sachets.
16. The original article mistakenly stated that each serve of soft drink was linked to a increased risk of liver cancer,
but it was actually each additional serve per week.17. Aspartame is commonly found in drinks such as Coke Zero, Diet Coke, Pepsi Max, and some home brand offerings.
18. The International Agency for Research on Cancer (IARC) has classified aspartame as a carcinogenic hazard to humans.
19. Aspartame is also used in food products like yogurt and confectionery but is not stable at warm temperatures and thus not used in .
20. Aspartame has commercial names such as Equal, Nutrasweet, Canderel, and in Australia.
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